Our new formulation design is a novel triple layered tablet dosage form based on multi-layered tablet technology and the desired surface area exposure per unit time. The new formulation is highly laminated with hydrophilic matrices in order to achieve a designed drug release profiles, such as zero order, first order and multi-modal, by varying the dissolution of drug content between the layers and the polymer concentration.

Multilayered tablets readily lend themselves to repeat-action products, wherein one layer of the layered tablet or the outer tablet of the compression coated tablet provides the initial dose, rapidly disintegrating in the stomach. The inner tablet is formulated with components that are insoluble in gastric media but release in the intestinal environment.
Layering in the tablet is one of the realistic means of gaining a better management on release profile. It is a viable alternative to conventional matrix tablets to circumvent the initial burst release and to achieve zero-order release profile.